The Chiefs defense is giving up an average of 323.6 pass yards per game, and have permitted 18 passing touchdowns through eight games this season. While running will be important to keep the Chiefs off balance, success will likely come from throwing against them - not running.

Defense was certainly a hot topic for the Chiefs who are coming off a bye week, and their best performance of the season against the Raiders two weeks ago. Still it’s hard to believe that a team can address issues this large in one short week, and that should allow 49ers quarterback Jeff Garcia to light it up.

Garcia has six touchdown passes in the past two games, and is looking to get on pace for another 30 touchdown season. To do that he’ll need to throw for 18 touchdowns in the remaining 8 games, which is slightly more than two touchdowns per game, while still sustaining his low number of interceptions.